Caused by a large pox virus, these smooth-walled, dome-shaped, pearly papules, 2 to 5 mm in size, have an umbilicated center. Occasionally a significant inflammatory reaction will occur. Principal sites are face, hands, lower abdomen, and genitals. A common viral infection seen in AIDS. It is more difficult to eradicate in these patients.
Usually intensely itching intradermal vascular reaction (wheals or hives). No epidermal changes such as scaling, papules, or blisters. More often has an unknown, nonspecific etiology, but can be related to medications, foods, and similar vascularstimulating agents. Laboratory studies are not likely to be helpful in evaluation unless there are suggestive findings in the history and physical examination.
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